Berzins, Stuart (Prof)

stuart Berzins

Position:Professor, Immunology
Discipline:Science
Phone:03 5327 9828
Email:s.berzins@federation.edu.au

Qualifications

  • B.Sc (1st Class Hons) (Monash Uni)
  • PhD (Monash Uni)
  • GCUT (UniMelb)

Teaching area

  • Immunology

Professional associations

  • Australia and New Zealand Society of Immunology (previously State Councilor and National Secretary)
  • 2008, 2010-ongoing Committee Member, Immunology Group of Victoria (IgV).
  • 2018-ongoing Committee Member, Melbourne Immunotherapy Network (MIN).
  • 2019-ongoing  Member of NHMRC Grant Review Panel (GRP) for Project/Ideas grant schemes.
  • 2023-2025 Member of Standing Research Subcommittee of the Victorian Cancer Council
  • 2022-ongoing  Member of Scientific Committee for Victorian COVID-19 Vaccinees Collection (VC2)

Research interests

  • Immunology – human immunology; tumor immunity; autoimmunity; T cell development and function

Publications

  • Gherardin NA….. Berzins SP…. Godfrey DI. (2018)

    • Human blood MAIT cell subsets defined using MR1 tetramers.

    Immunol Cell Biol. 2018 May;96(5):507-525. doi: 10.1111/imcb.12021.

    Journal Impact Factor: 5.1

  • Kling JC…. Berzins SP… Blumenthal A.

    • Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling.

    Front Immunol. 2018 Mar 16;9:483. doi: 10.3389/fimmu.2018.00483.

    PMID: 29616022

    Journal Impact Factor: 8.8

  • Nüssing S, … Berzins SP, … Kedzierska K.

    • Divergent SATB1 expression across human life span and tissue compartments.

    Immunol Cell Biol. 2019 Feb 25. doi: 10.1111/imcb.12233.

    Journal Impact Factor: 5.9

  • Kelly J, … and Berzins SP.

    • Chronically stimulated human MAIT cells are unexpectedly potent IL-13 producers.

    Immunol Cell Biol. 2019 Sep;97(8):689-699. doi: 10.1111/imcb.12281.

    Journal Impact Factor: 5.9

  • Koay HF… Berzins SP… Godfrey DI.

    • A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

    Sci Immunol. 2019 Nov 22;4(41). eaay6039. doi: 10.1126/sciimmunol.aay6039.

    PMID:31757835

    Journal Impact Factor: 30.8

  • Berzins S. P., Wallace M. E., Kannourakis G.,and Kelly J. (2020)

    • A role for MAIT cells in colorectal cancer

    Frontiers in Immunology 2020 May 20;11:949. doi: 10.3389/fimmu.2020.00949. eCollection 2020. PMID: 32508830

    Journal Impact Factor: 8.8

  • Mitchell J … Berzins S. P.*, and Kannourakis G* (*equal last authors).

    • Foxp3+ Tregs from Langerhans cell histiocytosis lesions co-express CD56 and have a definitively regulatory capacity.

    Clinical Immunology. 2020 Jun;215:108418. doi: 10.1016/j.clim.2020.108418. Epub 2020 Apr 10. PMID: 32283322

    Journal Impact Factor: 10.2

  • Wragg KM… Berzins S. P., … and Jennifer Ann Juno.

    • High CD26 and low CD94 expression identifies an IL-23 responsive Vδ2+ T cell subset

    with a MAIT cell-like transcriptional profile

    Cell Reports. 2020 Cell Rep. 2020 Jun 16;31(11):107773. doi: 10.1016/j.celrep.2020.107773. PMID: 32553157

    Journal Impact Factor: 8.8

  • Pellicci D. G., Koay HF, and Berzins S. P. (2020)

    • Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge.

    Nature Reviews Immunology2020 Jun 24. doi: 10.1038/s41577-020-0345-y. Online ahead of print.

    Journal Impact Factor: 108.6

  • Wesley T, Berzins S, Kannourakis G and Ahmed N

    • The attributes of plakins in cancer and disease: perspectives on ovarian cancer progression, chemoresistance and recurrence.

    Cell Commun Signal. 2021 May 17;19(1):55. doi: 10.1186/s12964-021-00726-x.

    PMID: 34001250

    Journal Impact Factor: 5.3

  • Evrard M….Berzins SP… Mackay LK.

    • Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes.

    J Exp Med. 2022 Jan 3;219(1):e20210116. doi: 10.1084/jem.20210116. Epub 2021 Oct 22. PMID: 34677611

    Journal Impact Factor: 17.6

  • Jalali, S.,Harpur CM, Piers AT, Auladell M, Perriman L, Li S, An K, Anderson J, Berzins SP, Licciardi PV, Ashhurst TM, Konstantinov IE, Pellicci DG.

    • A high-dimensional cytometry atlas of peripheral blood over the human life span.

    Immunol Cell Biol. 2022 Nov;100(10):805-821. doi: 10.1111/imcb.12594. Epub 2022 Nov 6. PMID: 36218032

    Journal Impact Factor: 5.9

  • Oh S, Liu X, Tomei S, Luo M, Skinner JP, Berzins SP, Naik SH, Gray DHD, Chong MMW Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential.

    • Front Immunol. 2023 Apr 3;14:1106652. doi: 10.3389/fimmu.2023.1106652. eCollection 2023. PMID: 37077921

    Journal Impact Factor: 8.8

  • Perriman L, …, Berzins SP*, Pellicci DG* (*co-last/corresponding authors).

    • A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus.

    Sci Immunol. 2023 Jul 21;8(85):eabo4365. doi: 10.1126/sciimmunol.abo4365. Epub 2023 Jul 14. PMID: 37450574

    Journal Impact Factor: 30.6