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Dr. Yutang Wang

Senior Lecturer, Biomedical Science

Science 03



Mt Helen Campus, Online


Dr Yutang Wang has broad research interest in investigating the pathogenesis of cardiovascular diseases including atherosclerosis, hypertension, diabetes, abdominal aortic aneurysm and heart hypertrophy.

Dr Wang received a research grant from the National Health and Medical Research Council in 2014, investigating the effect of renal sympathetic nerves on hypertension and atherosclerosis. He is also actively investigating the effect of uric acid on a range of diseases such as hypertension, diabetes and chronic kidney disease.

Yutang is a member of the American Heart Association and High Blood Pressure Research Council of Australia. He has published widely in peer-reviewed journals and is also an Editor of the journal Medicine.

Yutang is currently Senior Lecturer in biomedical science at Federation University Australia. He received his PhD in physiology in 2013.

Field of Research

  • Cardiology (incl. cardiovascular diseases)
  • Endocrinology

Animal Models, Pathogenesis, and Potential Treatment of Thoracic Aortic Aneurysm

Fasting Triglycerides in the Upper Normal Range Are Independently Associated with an Increased Risk of Diabetes Mortality in a Large Representative US Population

Fasting Triglycerides in the Upper Normal Range Are Independently Associated with an Increased Risk of Diabetes Mortality in a Large Representative US Population

Homeostasis Model Assessment for Insulin Resistance Mediates the Positive Association of Triglycerides with Diabetes

Postprandial Plasma Glucose between 4 and 7.9 h May Be a Potential Diagnostic Marker for Diabetes

Postprandial Plasma Glucose Measured from Blood Taken between 4 and 7.9 h Is Positively Associated with Mortality from Hypertension and Cardiovascular Disease

Special Issue: “New Trends in Diabetes, Hypertension, and Cardiovascular Diseases”

Special Issue “Sympathetic Nerves and Cardiovascular Diseases”

Association of constipation with increased risk of hypertension and cardiovascular events in elderly Australian patients

Dietary fatty acids and mortality risk from heart disease in US adults: an analysis based on NHANES

Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice

Fasting triglycerides are positively associated with cardiovascular mortality risk in people with diabetes

Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice

Prior cancer diagnosis and mortality profile in US adults

Sympathetic Nervous System and Atherosclerosis

Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations

The associations between high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP) or...

Both low and high levels of low-density lipoprotein cholesterol are risk factors for diabetes diagnosis in Chinese adults

Fasting status modifies the association between triglyceride and all-cause mortality: A cohort study

Hypouricemia is a risk factor for diabetes in Chinese adults

Late non-fasting plasma glucose predicts cardiovascular mortality independent of hemoglobin A1c

Mouse models for abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year....

Postabsorptive homeostasis model assessment for insulin resistance is a reliable biomarker for cardiovascular disease mortality and all-cause mortality

Stage 1 hypertension and risk of cardiovascular disease mortality in United States adults with or without diabetes

The uric acid value of 4.8?mg/dl may not be an ideal prognostic threshold for cardiovascular disease mortality

Tree nut consumption is associated with a lower risk of hyperestrogenism in men

A Modified MTS Proliferation Assay for Suspended Cells to Avoid the Interference by Hydralazine and ?-Mercaptoethanol

The 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium...

Definition, Prevalence, and Risk Factors of Low Sex Hormone-Binding Globulin in US Adults

Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys

Men have higher circulating levels of uric acid than women. This sex difference is suspected to...

Higher fasting triglyceride predicts higher risks of diabetes mortality in US adults

Background: It is unknown whether higher triglyceride results in higher mortality from diabetes,...

Hyperuricemia is independently associated with hypertension in men under 60 years in a general Chinese population

Hyperuricemia has been associated with hypertension, however, whether this association exists...

Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis

Men have higher circulating levels of uric acid than women. This sex difference is suspected to...

Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk

[No abstract available]

Reduced renal function may explain the higher prevalence of hyperuricemia in older people

This study aimed to investigate the contribution of renal dysfunction to enhanced hyperuricemia...

Tree nut consumption is associated with higher sex hormone-binding globulin levels in premenopausal US women

An Improved 3-(4,5-Dimethylthiazol-2-yl)-5-(3-Carboxymethoxyphenyl)-2-(4-Sulfophenyl)-2H-Tetrazolium Proliferation Assay to Overcome the Interference of Hydralazine

The MTS...

Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation

Singlet molecular oxygen (1O2) has well-established roles in photosynthetic plants, bacteria and...

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

Activation of the type 1 angiotensin II receptor (AT1) triggers proinflammatory signaling through...

Comment: Translating Guidelines Into Practice: Interpreting the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk

[No abstract available]

The concentration of ethanol affects its penetration rate in bovine cardiac and hepatic tissues

Introduction. Ethanol is a commonly used fixative. Fixation of the inner layers of the tissue...

The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

Methanol, ethanol and formalin are commonly used as fixatives to preserve biological tissues from...

Editorial: Function of renal sympathetic nerves

Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis

Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA)....

Renal denervation promotes atherosclerosis in hypertensive apolipoprotein E-Deficient mice infused with angiotensin II

Objective: To determine the effect of renal denervation (RDN) on the severity of atherosclerosis...

Resveratrol inhibits growth of experimental abdominal aortic aneurysm associated with upregulation of angiotensin-converting enzyme 2

Objective-Recent evidence suggests an important role for angiotensin-converting enzyme 2 (ACE2)...

The association between serum uric acid and blood pressure in different age groups in a healthy Chinese cohort

High serum uric acid (sUA) has been reported to be a risk factor for hypertension however,...

Wnt Signaling Pathway Inhibitor Sclerostin Inhibits Angiotensin II-Induced Aortic Aneurysm and Atherosclerosis

Objective-Sclerostin (SOST) has been identified as an important regulator of bone formation;...

A Peptide Antagonist of Thrombospondin-1 Promotes Abdominal Aortic Aneurysm Progression in the Angiotensin II-Infused Apolipoprotein-E-Deficient Mouse

Objective-Interaction of the activating sequence in thrombospondin-1 (TSP-1) with the conserved...

Letter by Wang regarding article, "efficacy and safety of catheter-based radiofrequency renal denervation in stented renal arteries"

[No abstract available]

Mouse models of intracranial aneurysm

Subarachnoid hemorrhage secondary to rupture of an intracranial aneurysm is a highly lethal...

Ambulatory blood pressure may be designed as the primary efficacy outcome in clinical trials on renal denervation

Angiotensin II, sympathetic nerve activity and chronic heart failure

Sympathetic nerve activity has been reported to be increased in both humans and animals with...

Could pathophysiology failure be ruled out?

Ethnicity and sympathetic tone: Predictors of the blood pressure response to renal denervation?

Influence of apolipoprotein E, age and aortic site on calcium phosphate induced abdominal aortic aneurysm in mice

Objective: To assess relevant features of abdominal aortic aneurysms (AAA) induced by calcium...

Is isolated systolic hypertension an indication for renal denervation?

[No abstract available]

It Is Urgent to Investigate Predictors of the Response of Blood Pressure to Renal Denerv

[No abstract available]

It may be not suitable to perform renal denervation in renal arteries with significant stenosis

[No abstract available]

Letter by Wang regarding article, "renal denervation for the treatment of cardiovascular high risk-hypertension or beyond?"

[No abstract available]

Limitations in current clinical trials on renal denervation

[No abstract available]

microRNA profiling in patients with abdominal aortic aneurysms: the significance of miR-155

AAA (abdominal aortic aneurysm) is a potentially life-threatening late-onset degenerative...

More research is needed to investigate the effect of denervation on blood pressure

[No abstract available]

Patients with renal artery stenosis may not be suitable for renal denervation

[No abstract available]

Renal artery stenosis may be responsible for the gradual return of high blood pressure after renal denervation

Renal denervation for resistant hypertension - The Symplicity HTN-1 study

[No abstract available]

Renal denervation: The Irish experience

[No abstract available]

  • Journals

Single-sided renal denervation may be not suitable for patients with significant renal artery stenosis

[No abstract available]

What is the true incidence of renal artery stenosis after sympathetic denervation?

Angiotensin converting enzyme 2 and atherosclerosis

Angiotensin converting enzyme 2 (ACE2) is a homolog of angiotensin converting enzyme (ACE) which...

Control of salt and volume retention cannot be ruled out as a mechanism underlying the blood pressure-lowering effect of renal denervation

[No abstract available]

Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: A critical role for heme oxygenase-1

Several lines of evidence indicate that quercetin, a polyphenol derived in the diet from fruit...

Neuronal nitric oxide synthase and sympathetic nerve activity in neurovascular and metabolic systems

Nitric oxide, derived from nitric oxide synthase (NOS), plays an important role in regulating...

The calcium chloride-induced rodent model of abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) affects similar to 5% men aged over 65 years and is an important...

Therapeutic effects of renal denervation on renal failure

Sympathetic nerve activity (SNA) is increased in both patients and experimental animals with...

Transforming growth factor-beta and abdominal aortic aneurysms

Abdominal aortic aneurysms (AAAs) are common problems in aged people which can be associated with...

Effects of coenzyme Q10 on vascular endothelial function in humans: A meta-analysis of randomized controlled trials

Objective: The purpose of this study was to quantify the effect of coenzyme Q10 on arterial...

Quercetin and its metabolites improve vessel function by inducing eNOS activity via phosphorylation of AMPK

Quercetin is a major flavonoid in a wide range of fruits and vegetables. Consumption of quercetin...

Representing ordered order-k Voronoi diagrams

The ordered order-k Voronoi diagram is a popular generalization of the ordinary Voronoi diagram...

  • Conference Proceedings

Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis

Objectives: To determine whether tryptophan metabolism to kynurenine contributes to the direct...

Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice

Indoleamine 2,3-dioxygenases-1 (Ido1) and -2 initiate the kynurenine pathway of tryptophan...

Interplay between heme oxygenase-1 and the multifunctional transcription factor Yin Yang 1 in the inhibition of intimal hyperplasia

Rationale: Induction of heme oxygenase (HO)-1 protects against experimental atherosclerotic...

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

Control of blood vessel tone is central to vascular homeostasis. Here we show that metabolism of...

Re: Cudihy D, Lee RV. 2009. the pathophysiology of pre-eclampsia: Current clinical concepts. Journal of Obstetrics and Gynaecology 29(7):576582

[No abstract available]