Ms. Priscilla Prestes
Centre Research Fellow
Four-week inhibition of the renin-angiotensin system in spontaneously hypertensive rats results in persistently lower blood pressure with reduced kidney renin and changes in expression of relevant gene networks
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets
Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension
DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies
Plasma lipocalin-2/NGAL is stable over 12 weeks and is not modulated by exercise or dieting
Amongst other immune cells, neutrophils play a key role in systemic inflammation leading to...
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
The kidney is an organ of key relevance to blood pressure (BP) regulation, hypertension and...
A guide to the short, long and circular RNAs in hypertension and cardiovascular disease
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in adults in...
DNA copy number variations - Do these big mutations have a big effect on cardiovascular risk?
[No abstract available]
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney
AIMS: Angiotensin-converting enzyme 2 (ACE2) is the cellular entry point for severe acute...
Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis
Objective: The male-specific region of the Y chromosome (MSY) remains one of the most unexplored...
Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics
Nephrons scar and involute during aging, increasing the risk of chronic kidney disease. Little is...
Best practice data life cycle approaches for the life sciences
Throughout history, the life sciences have been revolutionised by technological advances; in our...
Involvement of human monogenic cardiomyopathy genes in experimental polygenic cardiac hypertrophy
Hypertrophic cardiomyopathy thickens heart muscles, reducing functionality and increasing risk of...
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits
Genome-wide association studies (GWAS) have identified >100 loci of chronic kidney...
Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure
BACKGROUND: Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular...
Is there a link between mitochondrial DNA and blood pressure?
[No abstract available]
Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres
Leukocyte telomeres shorten with age, and excessive shortening is associated with age-related...
Muscle-Enriched MicroRNAs Isolated from Whole Blood Are Regulated by Exercise and Are Potential Biomarkers of Cardiorespiratory Fitness
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression...
Predicting biogeographical ancestry in admixed individuals - values and limitations of using uniparental and autosomal markers
When microsatellite profiles generated from crime scene samples do not match a known person, or...
Telomere dynamics during aging in polygenic left ventricular hypertrophy
Short telomeres are associated with increased risk of cardiovascular disease. Here we studied...
THE EFFECT OF GENES INVOLVED IN MONOGENIC HUMAN CARDIOMYOPATHIES IN A POLYGENIC MODEL OF CARDIAC HYPERTROPHY
NO Abstract
Tripartitemotif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22
Background:Left ventricular (LV) hypertrophy is a risk factor for cardiovascular death, but the...
Measurement of absolute copy number variation reveals association with essential hypertension
Background: The role of copy number variation (CNV) has been poorly explored in essential...
The SNPforID 34-Plex - Its Ability to Infer Level of Admixture in Individuals
Forensic scientists use genetic individualization markers to include or exclude persons of...
Evaluation of the IrisPlex System in Admixed Individuals
The prediction of externally visible characteristics (EVCs) is an important investigative tool...
Machado-Joseph disease Enhances genetic fitness: A Comparison Between Affected and Unaffected Women and Between MJD and the General Population