Dr. David Smith
Lecturer, Chemistry
Dr David Smith is a research chemist with an interest in the design, development and implementation of receptor and sensor arrays.
Both colorimetric and fluorescent sensing arrays have been created with applications including the analysis of environmental water samples to examine pollution, and the analysis of biological fluids to examine markers of health and disease. These arrays consist of cross-reactive sensors, and the resulting pattern response is analysed through statistical techniques such as principal component analysis and discriminant analysis.
David also has interests in chemical education research, particularly in the use of learning analytics as a tool to improve learning effectiveness.
David is a Lecturer in chemistry at the Gippsland campus at Federation University Australia. He completed his PhD at Durham University in the UK before moving to Australia in 2013, where he has undertaken several postdoctoral appointments, most recently working with the Open Source Malaria consortium in Sydney.
tele-Substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3- a]pyrazine-Based Antimalarials
We have discovered and studied a tele-substitution reaction in a biologically important...
Pattern recognition of toxic metal ions using a single-probe thiocoumarin array
Pattern recognition methods such as linear discriminant analysis and principal component analysis...
A reversible fluorescent probe for monitoring Ag(I) ions
Silver-containing nanomaterials are of interest for their antibiotic properties, for a wide range...
Deltamides and Croconamides: Expanding the Range of Dual H-bond Donors for Selective Anion Recognition
Dual H-bond donors are widely used as recognition motifs in anion receptors. We report the...
A coordination polymer for the site-specific integration of semiconducting sequences into DNA-based materials
Advances in bottom-up material design have been significantly progressed through DNA-based...
Fluorescent sensing arrays for cations and anion
Array-based sensing methods can be used to distinguish sets of similar analytes, by using a...
A library-screening approach for developing a fluorescence sensing array for the detection of metal ions
Detection of individual metal ions is of importance across a range of fields of chemistry...
Are two better than one? Comparing intermolecular and intramolecular indicator displacement assays in pyrophosphate sensors
Peptide receptors with Zn(ii)-DPA units and a covalently bound fluorescent coumarin indicator on...
Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes
Europium and terbium complexes of two structurally related ligands have been evaluated as optical...
Measuring equilibrium bicarbonate concentrations directly in cellular mitochondria and in human serum using europium/terbium emission intensity ratios
A series of Eu and Tb complexes of four different chiral ligands incorporating an azaxanthone...
Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells
Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the...
Development of responsive lanthanide probes for cellular applications
Useful probes of the intracellular environment are required for a wide range of bioactive species...