Dr. Yutang Wang
Phone: (03) 53279394
Position: Senior Lecturer
Discipline: Life Sciences
- PhD in Physiology, 2013
- Histopathology and Haematology (SCMED 3034), Molecular Cell Biology (SCMOL3001), Advanced Methods in Biotechnology(SCMOL3010), Research Projects
- Research Supervision: Dr Wang is currently supervising 4 PhD students (2 as principal supervisor and 2 as co-supervisor),1 master’s degree student and 1 Honours student.
- Member: American Heart Association, High Blood Pressure Research Council of Australia
- Editorial Board: Medicine, ISSN 0025-7974; Case Reports in Internal Medicine, ISSN 2332-7243
Yutang Wang specialises in the research field of sympathetic nerves and cardiovascular diseases. His research areas include sympathetic nerve functions, hypertension, atherosclerosis, abdominal aortic aneurysm, stroke and heart failure.
Publications (last 5 years)
Y Wang, K Lim, KM Denton, eds (2017). Function of Renal Sympathetic Nerves. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-295-8
M Dunster-Jones, M Steicke, J Mackie, R Guthrie, TN Din, F Ahmady, J Golledge and Y Wang. The concentration of ethanol affects its penetration rate in bovine cardiac and hepatic tissues. Folia histochemica et cytobiologica. 2018. doi: 10.5603/FHC.a2018.0009
M Steicke, G Yang, TN Dinh, M Dunster-Jones, O Sargisson, F Ahmady, J Golledge, Y Wang. The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin. European Journal of Histochemistry 2018; 62:2880
M Steicke, Y Wang. Comment: Translating Guidelines Into Practice: Interpreting the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk. Annals of Pharmacotherapy. 2018;52(1):91
W Cheng, S Wen,Y Wang, Z Qian, Y Tan, H Li, Y Hou, H Hu, J Golledge, G Yang. The association between serum uric acid and blood pressure in different age groups in a healthy Chinese cohort. Medicine. 2017;96 (50): e8953
C Moran, E Biros, S Krishna, Y Wang, C Tikellis, J Moxon, ME Cooper, P Norman, L Burrell, MC Thomas, and J Golledge. Resveratrol inhibits growth of experimental abdominal aortic aneurysm associated with upregulation of angiotensin converting enzyme 2. Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 doi.org/10.1161/ATVBAHA.117.310129
Y Wang, K Lim and KM Denton. Editorial: Function of Renal Sympathetic Nerves. Front. Physiol. 2017;8:642
Y Wang, T Dinh, A Nield, SM Krishna, K Denton and J Golledge. Renal denervation promotes atherosclerosis in hypertensive apolipoprotein E-deficient mice infused with angiotensin II. Front. Physiol. 2017; 8:215.
CS Moran, SW Seto, SM Krishna, S Sharma, RJ Jose, E Biros, Y Wang, SK Morton, J Golledge. Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis. Sci Rep. 2017;7:43079
SM Krishna, SW Seto, RJ Jose, J Li, SK Morton, E Biros, Y Wang, V Nsengiyumva, JHN Lindeman, GG Loots, CM Rush, JM Craig, J Golledge. The Wnt signalling pathway inhibitor sclerostin inhibits angiotensin II-induced aortic. Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) 2017;37:553-566.
Y Wang. Does renal denervation inhibit atherosclerosis in humans? Austin J Cardiovasc Dis Atherosclerosis. 2015; 2(1): 1013
A Cole, S Nankervis, H Chew, M Myers, F Charchar, Y Wang. Does renal sympathetic denervation decrease sympathetic nerve activity? Austin Journal of Neurosurgery. 2015;2(1): 1025
S Krishna, SW Seto, Roby Jose, E Biros, C Moran, Y Wang, P Clancy, J Golledge. A peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E deficient mouse. Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) 2015; 35:389-98
Y Wang. Letter by Wang Regarding Article, "Efficacy and safety of catheter-based radiofrequency renal denervation in stented renal arteries" Circulation: Cardiovascular Interventions. 2015;8:e002117.
Y Wang, TI Emeto, J Lee, L Marshman, C Moran, S Seto, and J Golledge. Mouse models of intracranial aneurysm. Brain Pathology 2015; 25:237-247
Y Wang. Is isolated systolic hypertension an indication for renal denervation? Frontiers in Physiology 2014;5:505.
Y Wang. Ethnicity and sympathetic tone: predictors of the blood-pressure response to renal denervation? Nature Reviews Cardiology 2014; 11:638.
Y Wang. Letter by Wang Regarding Article, “Renal Denervation for the Treatment of Cardiovascular High Risk-Hypertension or Beyond?” Circulation Research 2014; 115: e18
Y Wang. Could pathophysiology failure be ruled out? American Journal of Medicine 2014; 127:e29.
Y Wang. What is the true incidence of renal artery stenosis after sympathetic denervation? Frontiers in Integrative Physiology 2014; 5:311.
Y Wang. Ambulatory blood pressure may be designed as the primary efficacy outcome in clinical trials on renal denervation. International Journal of Cardiology 2014;176:1262–1263.
Y Wang. Single-sided renal denervation may be not suitable for patients with significant renal artery stenosis. Clinical Research in Cardiology 2014; 2014;103:950–951.
Y Wang, SM Krishna, J Moxon, TN Dinh, RJ Jose, H Yu, J Golledge. Influence of apolipoprotein E, age and aortic site on calcium phosphate induced abdominal aortic aneurysm in mice. Atherosclerosis 2014;235:204–12.
Y Wang. Renal denervation for resistant hypertension-the Symplicity HTN-1 study. Lancet 2014; 383:1885.
Y Wang. Renal denervation: the Irish experience. Hellenic Journal of Cardiology 2014;55:516.
Y Wang. It may be not suitable to perform renal denervation in renal arteries with significant stenosis. International Journal of Cardiology 2014;174:750.
Y Wang. Patients with renal artery stenosis may not be suitable for renal denervation. Clinical Research in Cardiology 2014;103:585–586.
Y Wang. Limitations in current clinical trials on renal denervation. International Journal of Cardiology 2014; 174:225.
Y Wang. Renal artery stenosis may be responsible for the gradual return of high blood pressure after renal denervation. Journal of Clinical Hypertension 2014; 16:313.
E Biros, CS Moran, Y Wang, PJ Walker, J Cardinal, J Golledge. MicroRNA profiling in patients with abdominal aortic aneurysms: the significance of miR-155. Clinical Science 2014;126:795–803.
Y Wang. More research is needed to investigate the effect of denervation on blood pressure. Hypertension 2014;63:e85
Y Wang. It is urgent to investigate predictors of the response of blood pressure to renal denervation. Canadian Journal of Cardiology 2014;30:465.e7
Y Wang, SW Seto and J Golledge. Angiotensin II, sympathetic nerve activity and chronic heart failure. Heart Failure Reviews 2014;19:187–198
Y Shen, NC Ward, JM Hodgson, IB Puddey, Y Wang, D Zhang, GJ Maghzal, R Stocker, KD Croft. Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipopfrotein E knockout mice fed a high-fat diet: A critical role for heme oxygenase-1. Free Radic Biol Med 2013;65:908–915.
Y Wang, K Denton, and J Golledge. Control of salt and volume retention cannot be ruled out as a mechanism underlying the blood pressure-lowering effect of renal denervation. Hypertension Research 2013;36:1006–7
Y Wang, SW Seto, J Golledge. Therapeutic effects of renal denervation on renal failure. Curr Neurovasc Res 2013;10:172–184
Y Wang and J Golledge. Neuronal nitric oxide synthase and sympathetic nerve activity in neurovascular and metabolic systems. Curr Neurovasc Res 2013;10:81–89.
Y Wang, S Krishna and J Golledge. The calcium chloride-induced rodent model of abdominal aortic aneurysm. Atherosclerosis 2013;226:29–39
Y Wang, C Tikellis, M Thomas and J Golledge. Angiotensin converting enzyme 2 and atherosclerosis. Atherosclerosis 2013;226:3–8.
Y Wang, S Krishna, PJ Walker, P Norman and J Golledge. Transforming growth factor-β and abdominal aortic aneurysms. Cardiovasc Pathol 2013;22:126–132.
Grants (last 5 years)
NHMRC project grant (APP1062671), 2014–2018: $291,688. Sole CI.